Andrew Huberman· PhD
so the challenge with making glp1 into a drug is that it has an extremely short halflife so it has a half life about 2 minutes in the blood um and so even if you inject people with glp1 it won't really be useful for anything
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so the challenge with making glp1 into a drug is that it has an extremely short halflife so it has a half life about 2 minutes in the blood um and so even if you inject people with glp1 it won't really be useful for anything
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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and the reason it's degrade is because there's an enzyme dpp4 is what it's called that degrades gp1
it produces a stabilized form of glp1 and its venom no one knows why one hypothesis is that it's something to do with the lizard uh as you said basically having this long time period between meals and it needs to regulate its blood glucose who knows if that is true but it turned out to be fortuitous because then this glp1 from this lizard it has a half life of like 2 hours