Consuming 300-400 grams of protein daily can be dangerous for individuals with urea cycle enzyme polymorphisms. — Whalespan
Consuming 300-400 grams of protein daily can be dangerous for individuals with urea cycle enzyme polymorphisms.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“there are cases of deaths in bodybuilders consuming in the range of you know three to four hundred grams of protein I mean it's an isolated case but if someone has a polymorphism in some of the enzymes in the urea cycle they could push quite they could push into that realm quite easily in the realm of bodybuilding and I think you're”
“I think that's more than anyone needs and my concern is that that actually is damaging and that that creates a stress on the urea cycle and requires the liver to to turn all of that nitrogen into urea and we know there are polymorphisms in genes like ornithine transcarbamylase so OTC that affect our capacity to turn nitrogen into urea”