Andrew Huberman· PhD
Emerging data from clinical trials points to potentially powerful use of psilocybin for the treatment of depression and certain forms of addiction, and perhaps compulsive disorders, too.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Emerging data from clinical trials points to potentially powerful use of psilocybin for the treatment of depression and certain forms of addiction, and perhaps compulsive disorders, too.
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and are pointing in the direction of psilocybin very soon, becoming a treatment for various forms of depression, including major depression.
Another category of treatments that's being actively explored now in laboratories and in the psychiatry realm are the psychedelics. And that's a huge category of compounds. However, one in particular, psilocybin is one that's being most intensely and actively pursued for its capacity to treat major depressive disorder.
But psilocybin is being explored as a clinical therapy in certain laboratory settings in particular, at Johns Hopkins School of Medicine. It's being explored in human patients for the treatment of major depression, for OCD I believe as well, but certainly for major depression and for eating disorders. And it seems from the initial wave of publications from that work done by the incredible Matthew Johnson or Dr. Matthew Johnson, who was a guest on this podcast before, he's also been on the Tim Ferris Podcast, he's been on the Lex Fridman Podcast. Dr. Matthew Johnson came on this podcast, he's talked about some of the work with psilocybin for the treatment of depression. Very impressive results there.
your laboratory is seeing phenomenal-- in my opinion, phenomenal results in the treatment of, otherwise, intractable depression, major depression, which so many people suffer from.
My read of the data on psilocybin is that it's still open to question but that some of the clinical trials show pretty significant recovery from major depression is pretty impressive but if we just set that aside and say okay more needs to be worked out for safety
there's some very very compelling clinical trials, psilocybin for major depression, maybe for uh other things as well.
But the point here is that these kinds of reorganizational experiences, it may be possible to embed them within different treatment contexts for different disorders like the psychosocial distress of cancer patients, and in this case, for addictions.