Andrew Huberman· PhD
Well psilocybin engages or increases serotonin transmission, meaning it increases the amount of serotonin, mainly by acting at these 5H2A receptors
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Well psilocybin engages or increases serotonin transmission, meaning it increases the amount of serotonin, mainly by acting at these 5H2A receptors
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Well, psilocybin, magic mushrooms, as it's sometimes called, mainly works on what's called the serotonin 5H2A receptor with some affinity for the 5HT1 receptor.
As a serotonergic agent, my understanding is it operates on these, is it the 5HT serotonin 2C receptor? - 2A.
what you're really talking about is a molecule of psilocybin that looks a lot like serotonin that is selectively and very strongly binding to and activating that serotonin to a receptor.
Certainly, we know that psilocybin binds serotonin 2A. We know different areas of brains that are activated and deactivated. We know something about the default mode network.