Bryan Johnson· Author
The same dose also disrupted the brain's functional connectivity by desynchronizing the default mode network (DMN) and its connection to the hippocampus—an effect three times greater than that of methylphenidate.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
The same dose also disrupted the brain's functional connectivity by desynchronizing the default mode network (DMN) and its connection to the hippocampus—an effect three times greater than that of methylphenidate.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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