Andrew Huberman· PhD
So a thousand milligrams per day is what you do. - Yeah and I had for about 15 years now. And you ingest that with some fatty substance, like olive oil or yogurt, is that right?
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
So a thousand milligrams per day is what you do. - Yeah and I had for about 15 years now. And you ingest that with some fatty substance, like olive oil or yogurt, is that right?
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I’m gonna keep mixing it with yogurt/olive oil.
Gonna keep taking it with some yogurt
Me: still taking resveratrol in yogurt
Resveratrol, one gram. - In the morning with yogurt or olive oil. - NMN as well. - A gram, yep. - Fisetin and quercetin. - Half a gram in the yogurt. - Spermidine. - Definitely spermidine in the morning, about a gram.
And so you take about a gram of resveratrol every day. I do and I've been taking that since about 2004. But like I said, you can't just put it in water and drink it. You have to add some fat to it. Yeah, so I typically have some yogurt, a couple of spoonfuls, not a lot because I'm trying to fast until dinner, but I could mix it with olive oil. Olive oil, recently, as we mentioned earlier in a previous episode, seems to be really good for activating sirtuins, but also you can dissolve resveratrol in it.
And the calculation for a mouse, which is called the alometric scaling, is about 12. So you multiply. Let's say if the mouse has 100 mg, 1.2 g for a human. For a rat, it's three. For a mini pig, it's one to one. Turns out we have about the same surface area as a mini pig. >> And so you take about a gram of resveratrol every day. >> Uh I do. And I've been taking that since about 2004. And uh I but I but like I said, it's you can't just put it in water and drink. >> You got to add some fat to it. >> Yeah. So I I typically have some yogurt, a couple of spoonfuls, not a lot cuz I'm trying to fast until dinner. Uh, but I could mix it with olive oil.
you still take risperidone Mike Lee that there's any harm and you said you take how much about a gram well that so my calculation is this first of all I'm I like experimenting that's you know I'm not afraid of death that's for sure but I want to be the first person to know if there's problems so I'm also keenly aware that what's gonna happen to all of us if we don't do anything is not pretty either hmm and so what have I got to lose it's cheap I've got buckets of it mine in my basement there's been never any sign of toxicity it's been in humans for a long time now take your risk it would seem is what if you're not taking enough sure but you know what one gram I think if it's not if it's not working at a gram then it's not working I don't think it's worth going higher
the amount that we're giving the mice and human studies it's a lot it's hundreds of times more than that so you can't drink your way into enough for a sparrow at all
The molecule I take a gram of resveratrol in the morning it's high dose it seemed to be fine
But resveratrol, I still take resveratrol, probably a gram or so every morning. [...] Yeah. In my yogurt. I don't measure it out, I just shake it in. So it might be half a gram to a gram.