Paul Saladino· MD
Soybean oil increases Lp-PLA2 in HUMAN trials. (PMID 28503188)
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Soybean oil increases Lp-PLA2 in HUMAN trials. (PMID 28503188)
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Soybean oil (full of linoleic acid) has ALSO been shown to increase LpPLA2 in humans, a lipoprotein associated phospholipase A2 that does the same things (cleaves PUFA from the sn-2 position of phospholipids), and a known biomarker of cardiovascular and metabolic diseases. (PMID: 28503188)
I found a paper saying that uh soybean oil elevated LP-PLA2.
So, it is it it sounds like you believe it does have some clinical utility and a finding like this might be sort of something to pay attention to. This is impact of an 8-week linoleic acid intake in soy oil on LP-PLA2 in active healthy activity in healthy adults. And the conclusion, an increase in plasma linoleic acid following intake of soy oil was independently associated with LP-PLA2 activity, which was also related to apoB, oxLDL and CEPICT, which is I believe is a measure of um endothelial function, this collagen epinephrine closure time.
an increase in plasma linoleic acid following intake of soybean oil independently associated with lppla2 activity which was also related to apob Ox LDL and c-e-p-i-ct which is collagen epinephrine closure time an indicator of endothelial functions
an increase in plasma linoleic acid following intake of soybean oil independently associated with lppla2 activity which was also related to apob Ox LDL and c-e-p-i-ct which is collagen epinephrine closure time an indicator of endothelial functions
there's a study in humans showing that soybean oil consumption increases lppla2 so lipoprotein phospholipase A2 is a particle associated with LDL that is involved in cleaving oxidized phospholipids and LDL
there's a study in humans showing that soybean oil consumption increases lppla2
and soybean oil has even been shown to increase lpp2 it's a technical name for a enzyme that Cleaves a fatty acid from a phospholipid when that fatty acid is oxidized so lpa2 is a risk factor for cardiovascular disease