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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
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Do seed oils pose an increased risk for heart disease? — Whalespan

Content›Video›Do seed oils pose an increas…

Do seed oils pose an increased risk for heart disease?

Paul Saladino9m · 2023-02-01

Claims Made

14

Claims Supported

12

Support Rate

86%

Support rate

12 of 14 claims supported

12 supported2 partial / not

Claims from this content

14

✓Well SupportedIncreasing saturated fat and decreasing polyunsaturated fat intake is associated with lower plasma concentrations of lipoprotein(a) and oxLDL-EO6.✓Well SupportedSoybean oil increases lipoprotein-associated phospholipase A2 (LpPLA2) in humans.✓Well SupportedSubstituting monounsaturated fats for saturated fats may be preferable for preventing atherosclerosis compared to substituting polyunsaturated fats.✓Well SupportedAnimal fats are preferred for cooking because they are low in linoleic acid and are more nutrient-dense than plant oils.Partially Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

LDL oxidation appears to be a strong marker for atherosclerosis.

◐Partially SupportedOxidized LDL, LP-little-a, and thiobarbituric acid reactive substances can promote inflammation and heart disease.

◐Partially SupportedPolyunsaturated fats are likely not as detrimental as historically believed, but are likely not as beneficial as monounsaturated fats.

◐Partially SupportedReplacing seed oils with animal fats is a beneficial dietary change.

◐Partially SupportedDiets rich in monounsaturated fatty acids (MUFAs) resulted in a lower tendency toward lipid peroxidation compared to diets rich in polyunsaturated fatty acids (PUFAs).

◐Partially SupportedDiets high in polyunsaturated fats (like seed oils) make LDL more susceptible to oxidation compared to diets rich in oleic acid or saturated fats.

◐Partially SupportedSeed oils are harmful to humans and increase the risk of cardiovascular disease.

◐Partially SupportedCare should be taken when advising on polyunsaturated fatty acid intake, and adequate antioxidant intake may be important to prevent oxidative stress.

◐Partially SupportedSeed oils are linked to diseases including cancer, diabetes, asthma, and arthritis.

◐Partially SupportedDietary intake of polyunsaturated fatty acids may adversely affect indices of lipid peroxidation and increase oxidative stress, despite potentially lowering cholesterol.