GLP-1 agonists like semaglutide and tirzepatide can reliably modulate hunger response.

“i think, OMIC really, did change, the, game, that, it, can, change, a fundamental, part, of, being, human, which, is the, hunger, response, huge, and, you, just get, a, shot, and, so, like, other, primal things, we, have, like, the, want, for, sex, and the, right, like, all, these, basic, needs, we have, and, now, we, can, basically, reliably modulate, them, turn, dial, yeah, and, so, it's and, even, turn, up, right, on, certain, things so, it's, it's, uh, actually, pretty remarkable”