High doses of Vitamin B6 may exacerbate peripheral neuropathy in some individuals. — Whalespan
High doses of Vitamin B6 may exacerbate peripheral neuropathy in some individuals.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“I think for people who have diabetic neuropathy you need to be careful with vitamin B6 check with your doctor. I was told, although I haven't found the literature on this that it can, in some cases exacerbate peripheral neuropathy, but for most people it's thought to be reasonably safe but again, always check with your physician”
“But I've also heard that vitamin B6 can be neurotoxic, especially in the periphery, that it can cause peripheral neuropathies if it's taken at high doses.”
“but there is evidence that having excessively high levels of B6 or supplementing with excessively high levels of B6 can cause some peripheral neuropathy, some death of nerves in the periphery.”