Alpha GPC increases acetylcholine synthesis, and Huperzine A inhibits its breakdown, both serving to increase net acetylcholine levels.

“Alpha GPC is in the choline pathway, such that more acetylcholine is synthesized after you ingest it. That's the general logic or framework of how it works. Whereas Huperzinene is mainly in the enzymatic pathway. It tends to adjust how much acetylcholine is broken down and lead to net increases in acetylcholine.”