The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
But a general normal dosing range, especially for someone starting, is around 100 to 120 milligrams divided over the course of a week, usually either every other day or three times a week-- occasionally, twice a week. Many people with SHBG a bit higher can get away pretty easily with twice a week.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
very unusual that I would ever start a patient anything more than 50 milligrams twice a week
very unusual that I would ever start a patient anything more than 50 milligrams twice a week