Andrew Huberman· PhD
And with testosterone, you want to get either testosterone and an SHBG or a free testosterone.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And with testosterone, you want to get either testosterone and an SHBG or a free testosterone.
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the reason we think about sex hormone-binding globulin is because it binds up free hormones and there is the possibility that free hormones are the active hormones and so we can't just get total hormones we have to get the the free and the total
is free testosterone low because testosterone is low or because sex and we're binding globulin is high because free testosterone which is what matters is proportional to testosterone and inversely proportional to sex and we're binding globulin
I need to know their sex and we're binding globulin their estrogen yeah free testosterone is really what we're trying to fix