The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Nicotine is called nicotine because acetylcholine binds to the nicotinic receptor. There are two kinds of acetylcholine receptors, muscarinic and nicotinic, but the nicotinic ones are involved in attention and alertness.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Today it's really simple. Nicotine only binds to the nicotinic acetylcholine receptors and there are a bunch of different ones on a bunch of different tissues.
But, nicotine from tobacco binds that same receptor, but with much greater affinity, and therefore also creates a state of focus, but a much greater one than we can achieve without nicotine.