Andrew Huberman· PhD
There's been a lot of different meta analyses of all-cause mortality studies, where vitamin D levels really seem to be ideal between 40 to 60 nanograms per milliliter.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
There's been a lot of different meta analyses of all-cause mortality studies, where vitamin D levels really seem to be ideal between 40 to 60 nanograms per milliliter.
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there's been a lot of different metaanalyses of all cause mortality studies where vitamin D levels are are really seem to be ideal between 40 to 60 nanogs per milliliter.
People who have about 40 to 60 ng/mL per milliliter of vitamin D in their blood tend to have the lowest mortality.
Meta-analyses have found that serum levels of 40-60 ng/ml are linked to the lowest all-cause mortality.
It disagrees with 32 other studies finding lowest all-cause mortality levels 40-60 ng/ml.
Largest study (1966-2013) found levels 40-60ng/ml associated w/lowest all-cause mortality.
...above 60ng/ml is linked to higher all-cause mortality.
40-60ng/ml was the range specifically correlated with having decreased all-cause mortality in a recent study
levels of 40-60 ng/ml assoc. w/lowest mortality.
Goes against 33 studies showing levels of 40-60 ng/ml assoc. w/lowest mortality.
Blood levels bet. 40-60 ng/ml linked to lowest all-cause mortality (33 diff studies).
In two separate large studies 40-60 ng/ml was associated with lowest all-cause mortality.
40-60 ng/ml is associated with lowest all-cause mortality.
All‑cause mortality risk is elevated below 30 ng/mL and improves most as vitamin D levels rise to roughly 30–40 ng/mL, with minimal additional benefit above that range.
40-60 ng/ml is best range based on lowest mortality.
another piece of evidence that vitamin D regulates the aging process comes from a recent study that found that individuals in the highest quartile of vitamin D which was between 40 and 60 nanograms per milliliter actually had an increased life span
there's about 31 different studies in the literature that show people that have vitamin D levels between 30 and 60 40 to 60 nanograms per milliliter have the lowest all-cause mortality including cardiovascular disease neurogenerative disease and cancer
And what the meta-analysis found is that people that had blood levels between 40 and 60 nanograms per milliliter had the lowest all-cause mortality compared to those that, you know, had lower vitamin D levels or even really, really high ones.
Back in 2013, there was a meta-analysis published, I don't know the author's name, but the studies dated back from the 1960s to the 2013. And it was looking at all-cause mortality in association with vitamin D blood levels. And it was found that you know, levels, somewhere between 40 to 60, or 70, like was the lowest all-cause mortality.
And it's, it's, you know, pretty clear that having levels above 30 is associated with a lower all cause mortality.
I think going above 60 nanograms per milliliter is probably still okay like going to 80 you know like there's there's studies looking at 80 and it's still associated with lower all cause mortality
and it seems as though The Sweet Spot for vitamin D is between 40 to 60 nanog per milliliter and um you know there's there's all cause mortality studies also looking at vitamin D levels there's metaanalyses of these you know ranging for from 1960s all the way to the you know mid like 2015 and it's it's really it seems like 40 to 60 is a really good sweet spot for the lowest all cause mortality with vitamin D