Andrew Huberman· PhD
There's been studies looking at vitamin D receptor knockout mice. And I use this a lot in my presentations when I'm talking about vitamin D and longevity. If you look at these animals, the vitamin D receptor, as I mentioned earlier, vitamin D binds to the receptor, and then it complexes with the retinoid receptor, and they go into the nucleus as a complex and turn on and turn off genes. Well, if you get rid of that receptor, which is what you can do in animal studies, you can determine what effects there will be with no vitamin D.