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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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What aspect of women’s health is the least studied or understood? (AMA #3) — Whalespan

Content›Video›What aspect of women’s healt…

What aspect of women’s health is the least studied or understood? (AMA #3)

Peter Attia11m · 2020-01-24

Claims Made

15

Claims Supported

10

Support Rate

67%

Support rate

10 of 15 claims supported

10 supported5 partial / not

Claims from this content

14

✓Well SupportedTwo out of three Alzheimer's cases are women.✓Well SupportedEven pre-menopause, women can have higher testosterone than estrogen when units are converted to be comparable.✓Well SupportedThe rapid reduction of progesterone in the last seven days of a woman's menstrual cycle can cause PMS symptoms.◐Partially SupportedTestosterone levels in premenopausal women are 10-50 times higher than estrogen and progesterone levels when converted to equivalent units.✕Not Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

The Women's Health Initiative study, which discouraged hormone replacement therapy for women, represents a major failure of the medical field.

✕Not SupportedMany doctors disregard menopausal and perimenopausal symptoms and incorrectly advise against hormone replacement therapy.

◐Partially SupportedWomen tend to have less cardiovascular disease than men, even after accounting for ApoB, LDL-C, blood pressure, and smoking.

◐Partially SupportedWomen with altered peripheral T4 metabolism after childbirth, despite normal TSH, may experience low energy levels.

✓Well SupportedWomen in their fifth decade typically experience a shutdown of estrogen, progesterone, and testosterone production.

◐Partially SupportedMen experience a more gradual decline in sex hormones compared to women, making symptomatic changes harder to notice.

◐Partially SupportedTherapeutic phlebotomy has a greater effect on individuals who are more metabolically deranged, reducing oxidative stress from iron.

✕Not SupportedThe higher prevalence of Alzheimer's disease in women is unlikely to be solely due to age or increased longevity.

◐Partially SupportedLower iron levels in women due to menstrual cycles may offer a protective benefit against heart disease.

◐Partially SupportedWomen have historically been understudied in medical research, leading to assumptions that findings in men apply to women.