Increased daily caloric intake to 2250 calories, up from 2000. Goal: increase facial fat.

Well SupportedBryan Johnson's caloric intake was reduced to 1,950 calories per day, leading to fat loss.

Partially SupportedA daily intake of 2250 calories represents 10% caloric restriction optimal nutrition for males.

Partially SupportedBryan Johnson's 500-day Heart Rate Variability (HRV) gains, achieved with 20% CRON, have remained constant with 10% CRON.

Partially Supported10% caloric restriction optimal nutrition may be as effective for longevity as 20% caloric restriction optimal nutrition.

Partially Supported