As we age, the brain responds to declining metabolic efficiency by cutting energy to organ

Well SupportedBryan Johnson's body temperature runs approximately 3°F cooler than average due to his diet and protocol.

Partially SupportedAs we age, the brain reduces energy supply to organs, including muscles and itself, leading to fatigue, muscle wasting, and cognitive decline.

Well SupportedLowering constitutive core body temperature may slow aging by slowing all metabolic processes.

Partially SupportedOptimizing metabolism through sleep, nutrition, exercise, stress management, and social support can preserve brain health.