A human premature egg just “taught” a skin cell how to divide like one. A milestone to lab

Partially SupportedTransferring the nucleus from a skin cell into an egg is an alternative approach to in vitro gametogenesis that bypasses the need to reprogram the skin cell.

Partially SupportedIn an experiment, nuclei retained an average of 22.8 chromosomes after division, with many imperfect splits, whereas normal egg formation splits 46 chromosomes into 23.

Partially SupportedRandom chromosome segregation occurred in the experiment without genetic crossover.

Partially SupportedThe nucleus of adult skin cells can be coaxed by the egg's machinery in premature eggs to halve its chromosomes through a process called 'mitomeiosis'.

Partially Supported