Late-night eating and melatonin may impair insulin response

Well SupportedMelatonin may make pancreatic islet cells less responsive to glucose, leading to reduced insulin production and release, which can cause elevated blood sugar levels.

Well SupportedHigher fasting blood sugar levels are associated with greater loss of brain volume in the hippocampus and amygdala.

Well SupportedMelatonin receptor and clock genes are significant factors influencing obesity and diabetes.

Partially SupportedFinish the last meal or consumption of blood-sugar-raising substances up to three hours before bedtime to reduce insulin production.

Partially Supported