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Weekly · Sunday Morning

Five longevity claims.
Worth your time.
Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

5 audits·1 verdict change·0 affiliate links·Every Sunday

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Charting the Architecture of the Universe & Human Life | Dr. Brian Keating — Whalespan

Content›Video›Charting the Architecture of…

Charting the Architecture of the Universe & Human Life | Dr. Brian Keating

Andrew Huberman3h 8m · 2025-01-20

Claims Made

288

Claims Supported

241

Support Rate

84%

Support rate

241 of 288 claims supported

241 supported47 partial / not

Claims from this content

73

✓Well SupportedAG1 is a vitamin, mineral, probiotic drink with adaptogens designed to meet foundational nutritional needs and provide insurance for adequate fruit and vegetable intake.✓Well SupportedAndrew Huberman drinks Athletic Greens twice a day, typically once in the morning and again in the afternoon or late afternoon, mixed with water and lemon or lime juice.✓Well SupportedComprehensive blood testing is vital for detecting many aspects of mental and physical health, and Function Health offers this affordably.✓Well SupportedFunction offers over 100 advanced lab tests for comprehensive bodily health assessment.Well Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Andrew Huberman dissolves one packet of Element in 16-32 ounces of water upon waking and during exercise for hydration and electrolyte intake.

✓Well SupportedHelix Sleep mattresses and pillows are tailored to individual sleep needs assessed through a quiz.

✓Well SupportedThe book 'Protocols: An Operating Manual for the Human Body' offers scientifically substantiated protocols for sleep, exercise, stress control, and focus/motivation.

✓Well SupportedAG1 supports the gut microbiome, which in turn supports the immune system and the gut-brain axis, impacting mood, energy, focus, and overall mental and physical health.

✓Well SupportedThe Helix Dusk Mattress is reported to improve sleep depth, duration, and quality.

✓Well SupportedEffective therapy provides rapport with a trusted individual, emotional support or directed guidance, and useful insights that can lead to significant life improvements.

✓Well SupportedTaking AG1 daily improves physical health, mental health, and cognitive and physical performance, as evidenced by noticeable differences during lapses in use.

✓Well SupportedMattress characteristics like softness, firmness, and breathability significantly impact sleep quality and should be tailored to individual needs.

✓Well SupportedHydration and adequate electrolyte intake are critical for optimal brain and bodily function, as even slight dehydration can diminish cognitive and physical performance.

✓Well SupportedRoka red lens glasses can be worn in the evening after sunset to filter out short-wavelength light that suppresses melatonin secretion and can alter sleep.

✓Well SupportedSleep is fundamental to mental health, physical health, and performance, and an ideal sleep environment is key to achieving excellent sleep.

✓Well SupportedRegular therapy is as important for overall health as regular exercise.

✓Well SupportedAG1 is offering a free one-month supply of Omega-3 fish oil and a bottle of vitamin D3 plus K2 with subscription orders placed via drinkag1.com/huberman.

✓Well SupportedConsuming leafy greens and supplementing with N-acetylcysteine (NAC) can support glutathione production, detoxification, and reduce mercury levels.

✓Well SupportedElement's chocolate medley can be mixed with hot water for hydration and electrolyte replenishment in cold, dry weather.

✓Well SupportedIt is difficult to obtain sufficient vitamins, minerals, micronutrients, and adaptogens from diet alone.

✓Well SupportedMelatonin levels are inversely correlated with day length, with longer days leading to less melatonin release and shorter days leading to more.

◐Partially SupportedLarge, rapid increases in dopamine not preceded by effort can lead to a subsequent trough that diminishes the will to live.

◐Partially SupportedAdaptogens are compounds that improve the body and brain's ability to buffer against stressors.

◐Partially SupportedFunction Health identified elevated mercury levels and recommended limiting tuna, increasing leafy greens, and supplementing with NAC.

◐Partially SupportedSome species, including turtles, migrating birds, and fruit flies, possess magnetoception (the ability to sense magnetic fields).

◐Partially SupportedDark sky communities forbid upward-shining light and require narrow spectral bands for lighting.

◐Partially SupportedThe duration of melatonin release is directly related to the amount of ambient light, with light suppressing melatonin.

◐Partially SupportedThe average menstrual cycle length is 28 days and is influenced by the lunar cycle.

◐Partially SupportedSome women can accurately estimate their ovulation timing to within a couple of hours, and some report feeling ovulation.

◐Partially SupportedThe human brain's ability to occupy different time perceptions can lead to being taken out of the present moment.

✕Not SupportedAstrology is not supported by evidence and performs worse than random chance in predictions.

◐Partially SupportedDelighting in everyday things is as important as engaging with high-level concepts.

✓Well Supported20/20 vision corresponds to approximately 60 cycles per degree of visual acuity.

◐Partially SupportedThe apparent angular diameter of the Moon is approximately half a degree, which is the same size as the Sun from Earth.

◐Partially SupportedLight cannot penetrate the skull to stimulate the pineal gland, nor can light introduced into the ears or mouth.

◐Partially SupportedThe microbiome is more numerous than human cells and is powerful for modulating biological processes.

◐Partially SupportedThe human brain functions as a prediction-making machine that favors confirmation bias unless trained as a scientist.

◐Partially SupportedSome reptiles and birds have thin skulls allowing light to directly reach the pineal gland.

◐Partially SupportedHuman pineal gland information about environmental light is relayed through the eyes via a specific neural pathway.

◐Partially SupportedThe green flash phenomenon may be explained by the opponency of human color perception, where prolonged red/orange light exposure leads to a subsequent perception of green.

◐Partially SupportedMothers contracting influenza during the second trimester may be correlated with a heightened probability of schizophrenic offspring.

◐Partially SupportedHumans are born with two built-in refracting telescopes (eyes) that function as astronomical detection tools.

◐Partially SupportedCharting time by observing the sky at night is meaningful for tracking temporal changes.

◐Partially SupportedGenetics play a more significant role in human traits than is often acknowledged.

◐Partially SupportedThe Snellen chart is a standard for measuring visual acuity.

✕Not SupportedConfirmation bias requires active guarding.

◐Partially SupportedThe scientific method, as practiced, relies on hypothesis, observation, experimentation, and iteration.

◐Partially SupportedThe Gutenberg Bible provided a calibration standard for visual acuity in Western Europe approximately 430 years ago, based on the fixed size of its printed characters.

✕Not SupportedConfusing correlation with causation is dangerous and can lead to negative outcomes.

◐Partially SupportedWater molecules absorb microwaves, which is the principle behind microwave ovens heating food.

◐Partially SupportedThe season of birth can impact a child, with factors like proximity to the equator influencing outcomes.

◐Partially SupportedMaternal influenza infection during the second trimester of pregnancy is associated with an increased probability of schizophrenic offspring.

◐Partially SupportedBeing wrong for the right reasons in science, meaning not engaging in P-value hacking or data fudging, is important for scientific progress.

◐Partially SupportedAdaptive Optics, borrowed from astronomy, is used in neuroscience microscopy to achieve higher resolution by utilizing environmental noise.

◐Partially SupportedThe ability to see around corners can be achieved by shining lasers at the most visible location near the target and capturing reflections.

◐Partially SupportedSeason of birth correlates with health outcomes due to food availability and infectious disease prevalence.

✕Not SupportedP-hacking, manipulating data after collection to achieve statistical significance, is unethical.

◐Partially SupportedThe width of a thumb held at arm's length approximates one degree of visual angle.

◐Partially SupportedThe sun's light peaks in the green wavelength range, approximately 450-550 nanometers.

◐Partially SupportedThe survival probability of human infants and mothers is strongly dictated by the availability of resources, which is influenced by seasonal changes in day length.

◐Partially SupportedThe human eye perceives lines as solid black when there are 40 black lines and 40 light spaces per degree due to acuity limits.

◐Partially SupportedA functional clock that worked across different time zones and conditions was not available until the 1700s.

◐Partially SupportedThe human prefrontal cortex enables the ability to forecast and model future outcomes.

◐Partially SupportedAdaptive Optics technology from astronomy is applied in ophthalmology to image the back of the eye.

◐Partially SupportedHigher numerical aperture in microscopes allows for better resolution, enabling the observation of smaller details.

◐Partially SupportedInteractions with others, dirt, or pets change the microbiome.

◐Partially SupportedThe human microbiome influences fatty acid and neurotransmitter production.

◐Partially SupportedHumans and other species may be vehicles for the microbiome, which seeks to propagate itself.

◐Partially SupportedThe menstrual cycle, averaging 28 days, has no documented relationship with the lunar cycle.

◐Partially SupportedA past scientific error was due to an unaware confounder, not fabricated data.

◐Partially SupportedThe human eye functions as a refracting telescope, allowing for judgments about space and time based on relative positions and movements.

◐Partially SupportedHumans share approximately 50% of their chromosomes with fruit flies.

◐Partially SupportedBonobos share approximately 98% of their genetic material with humans.