The first molecule to extend lifespan

Well SupportedEncapsulated rapamycin was effective in extending lifespan in both late middle-aged and younger mice.

Partially SupportedThe biology regulated by rapamycin, calorie restriction, and methionine restriction is the single best-validated biology across labs and species for influencing aging.

Partially SupportedMolecules like rapamycin act at a fundamental level of aging, unlike disease-specific drugs.

Partially SupportedA drug is considered anti-aging only if it demonstrates effects on multiple different age-sensitive properties, not just if it acts as a broad-spectrum anti-cancer agent.

Partially Supported