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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
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The Connection Between Obesity and Cancer — Whalespan

Content›Video›The Connection Between Obesi…

The Connection Between Obesity and Cancer

Peter Attia6m · 2021-12-15

Claims Made

11

Claims Supported

6

Support Rate

55%

Support rate

6 of 11 claims supported

6 supported5 partial / not

Claims from this content

9

✓Well SupportedInsulin resistance and inflammation are likely physiological drivers of cancer associated with obesity.◐Partially SupportedObesity is harder to disentangle from other causal factors for cancer compared to tobacco, as it is associated with different eating, sleeping, and exercise patterns.◐Partially SupportedObesity is causally related to cancer, although the relationship is complex due to multivariate factors.◐Partially SupportedMetabolically healthy obese individuals are not more likely to develop cancer.Partially Supported

More from Peter Attia

Peter Attia on Zone 2 Cardio

Peter Attia on Rapamycin (with Matt Kaeberlein)

Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

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Hyperinsulinemia is a growth factor associated with obesity that may drive cancer cell proliferation.

◐Partially SupportedCancer development likely requires both chromosomal insult and hyperinsulinemia.

◐Partially SupportedThe correlation between insulin and cancer is weaker than the correlation between smoking and cancer.

◐Partially SupportedTo prevent cancer, one should aggressively avoid hyperinsulinemia and metabolic ill health, and minimize DNA damage.

◐Partially SupportedInsulin resistance in thinner individuals correlates with cancer.