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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Options for testing your microbiome | Peter Attia & Colleen Cutcliffe — Whalespan

Content›Video›Options for testing your mic…

Options for testing your microbiome | Peter Attia & Colleen Cutcliffe

Peter Attia12m · 2023-12-27

Claims Made

17

Claims Supported

9

Support Rate

53%

Support rate

9 of 17 claims supported

9 supported8 partial / not

Claims from this content

10

◐Partially SupportedMicrobiome function, specifically the production of short-chain fatty acids like butyrate, propionate, and acetate, is a key indicator of gut health.◐Partially SupportedQuantitative PCR (qPCR) is more accurate than sequencing for determining the quantity of specific bacterial strains in the microbiome.◐Partially SupportedCombining short-read and long-read DNA sequencing provides more accurate and comprehensive analysis than either method alone.◐Partially SupportedBacterial gene copy number can affect substance metabolism, as seen with digoxin metabolism by a microbe.Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Bacteria can be viewed as enzymes in an in vitro reaction where a substrate is provided to produce short-chain fatty acids.

◐Partially SupportedShort-chain fatty acids (SCFAs) like butyrate, propionate, and acetate are key outputs of carbohydrate metabolism by gut bacteria.

◐Partially SupportedCommercial genetic tests can screen for hundreds of known polymorphisms (SNPs) to assess specific risks, such as cancer risk.

◐Partially SupportedUnderstanding baseline microbiome and its changes due to diet, travel, or antibiotics is crucial.

◐Partially SupportedShort-chain fatty acids like butyrate, propionate, and acetate are produced by bacteria from specific substrates.

◐Partially SupportedThe liver's P450 system and gut microbes are primary determinants of drug metabolism variability.