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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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How muscle growth works | Peter Attia & Andy Galpin — Whalespan

Content›Video›How muscle growth works | Pe…

How muscle growth works | Peter Attia & Andy Galpin

Peter Attia8m · 2023-08-19

Claims Made

11

Claims Supported

5

Support Rate

45%

Support rate

5 of 11 claims supported

5 supported6 partial / not

Claims from this content

9

◐Partially SupportedThe existence and nature of sarcoplasmic hypertrophy versus increases solely in contractile units was not definitively known until recently.◐Partially SupportedSarcoplasmic hypertrophy leads to size increases without corresponding strength gains.◐Partially SupportedHypertrophy training that compromises optimal actin-myosin spacing may lead to increased muscle size at the expense of potential strength.◐Partially SupportedOptimal force production from muscle requires a specific lattice spacing between myosin and actin, analogous to preload in the heart.Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Hypertrophy, in the context of muscle growth, primarily refers to an increase in the cross-sectional area or diameter of muscle fibers.

◐Partially SupportedOptimal force production in muscle fibers depends on the lattice spacing between actin and myosin filaments.

◐Partially SupportedThe difference in strength between bodybuilders and strongmen/weightlifters, despite similar muscle size, likely involves intracellular factors beyond neurological adaptations.

◐Partially SupportedPreserving muscle tissue fluid content without contamination or artifact was a challenge in studying hypertrophy.

◐Partially SupportedTwo-thirds to seventy percent of total body weight is water, with the majority of this water residing within the body's cells, including muscle tissue.