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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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What are Statins? — Whalespan

Content›Video›What are Statins?…

What are Statins?

Paul Saladino7m · 2022-09-03

Claims Made

11

Claims Supported

2

Support Rate

18%

Support rate

2 of 11 claims supported

2 supported9 partial / not

Claims from this content

9

◐Partially SupportedStatins are HMG-CoA reductase inhibitors that interrupt the mevalonate pathway, critical for cholesterol synthesis.◐Partially SupportedThe mevalonate pathway produces critical downstream intermediates beyond cholesterol, such as CoQ10, dolichol, and precursors for selenoproteins and vitamin K2.◐Partially SupportedDolichol is critical for insulin receptor function within caveolae in cell membranes.◐Partially SupportedIndividual health, longevity, and quality of life are primarily determined by diet, not solely by genetics.Not Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✕

Interrupting the body's biochemical cascades with medications like statins may not be wise.

✕Not SupportedMedical education often overlooks critical downstream intermediates of the mevalonate pathway, such as dolichol and those involved in selenoprotein synthesis and vitamin K2 formation.

✕Not SupportedAttributing illness solely to genetics is a significant lie in Western medicine that prevents positive lifestyle changes.

◐Partially SupportedLDL particles have critical roles in the human body that are often not taught in medical school, suggesting they may not be solely responsible for causing human disease.

◐Partially SupportedIsopentenyl pyrophosphate is required for selenoproteins like glutathione peroxidase and thioredoxin reductase, which manage oxidative-reductive state and vitamin K2 conversion.