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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Are non protein amino acids at the root of neurodegeneration? — Whalespan

Content›Video›Are non protein amino acids …

Are non protein amino acids at the root of neurodegeneration?

Paul Saladino9m · 2022-02-24

Claims Made

12

Claims Supported

6

Support Rate

50%

Support rate

6 of 12 claims supported

6 supported6 partial / not

Claims from this content

10

✓Well SupportedCutting the vagus nerve at the trunk (truncovagotomy) for severe gastritis is associated with a lower incidence of Parkinson's disease compared to selective vagotomy.◐Partially SupportedL-dopa from Mucuna pruriens may accelerate Parkinson's disease due to protein incorporation.◐Partially SupportedL-DOPA from Mucuna pruriens may promote protein aggregation and accelerate Parkinson's progression.◐Partially SupportedThe incorporation of non-protein amino acids into the human food chain may significantly contribute to neurodegenerative damage.Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Non-protein amino acids are found primarily in seeds, nuts, grains, and legumes.

◐Partially SupportedL-DOPA is present in the seeds of the genus Mucuna, which are highly insect-resistant.

◐Partially SupportedL-dopa, when incorporated into proteins, acts as an adhesive and cross-linking agent, capable of generating protein aggregates and preventing their removal by proteolysis.

◐Partially SupportedL-DOPA can be incorporated into proteins in Parkinson's patients, potentially accelerating Parkinsonism.

◐Partially SupportedLectins from legumes may move from the gut through the vagus nerve to the brain, potentially causing neurodegeneration in dopaminergic neurons.

✕Not SupportedInvestigating dietary factors like lectins for Parkinson's disease root cause may be more effective than relying solely on pharmaceuticals like l-dopa.