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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
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What Happens to Bones When You Stop Moving | Peter Attia AMA 37 — Whalespan

Content›Video›What Happens to Bones When Y…

What Happens to Bones When You Stop Moving | Peter Attia AMA 37

Peter Attia7m · 2025-07-13

Claims Made

11

Claims Supported

11

Support Rate

100%

Support rate

11 of 11 claims supported

11 supported0 partial / not

Claims from this content

8

✓Well SupportedBone loss due to disuse osteopenia is incremental, progressive with time, and occurs more rapidly in trabecular bone than cortical bone.✓Well SupportedBone loss in microgravity or partial paralysis can be approximately 2% per month, and up to 7% per month in cases of complete paralysis.◐Partially SupportedIn immobilized mice treated with botulinum toxin, bisphosphonates prevented bone loss in the femoral neck and upper femoral bone.◐Partially SupportedImmobility is a significant problem in aging populations.Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Immobility for two weeks in 65-year-olds can lead to a loss of approximately four pounds of lean mass, impacting bone mineral density.

◐Partially SupportedPhysical therapy that actively loads muscles is recommended to help mitigate bone density concerns during immobility.

◐Partially SupportedEven when immobilized for an injury, other muscles in the body can be moved and put under load, including isometrically.

◐Partially SupportedIsometric resistance against another person without movement is important for maintaining muscle load during immobility.