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Weekly · Sunday Morning

Five longevity claims.
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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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The mainstream understanding of PUFAs is built on faulty epidemiology — Whalespan

Content›Video›The mainstream understanding…

The mainstream understanding of PUFAs is built on faulty epidemiology

Paul Saladino5m · 2020-11-03

Claims Made

10

Claims Supported

6

Support Rate

60%

Support rate

6 of 10 claims supported

6 supported4 partial / not

Claims from this content

8

✓Well SupportedOnly 12.2% of the population surveyed in NHANES (2009-2016) were metabolically healthy.◐Partially SupportedIndigenous populations with lower incidences of cardiovascular disease and cancer consume high amounts of saturated fat and carbohydrates and do not eat seed oils.✕Not SupportedEpidemiological research conducted in metabolically unhealthy populations yields unreliable results.✕Not SupportedStandard laboratory reference ranges are based on statistical norms of sick populations, not healthy ones.Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Seed oils are a worse metabolic toxin than streptozotocin from a toxicological perspective.

◐Partially SupportedA diet high in n-6 PUFAs leads to significantly lower cardiolipin levels in mice compared to a normal diet.

◐Partially SupportedEpidemiological correlations observed in metabolically unhealthy populations may not be reflective of otherwise metabolically healthy individuals.

✕Not SupportedEpidemiological research on seed oils is flawed because it studies populations already consuming them for decades, not comparing them to non-consumers.