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Weekly · Sunday Morning

Five longevity claims.
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Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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How does VO2 max correlate with longevity? | The Peter Attia Drive Podcast — Whalespan

Content›Video›How does VO2 max correlate w…

How does VO2 max correlate with longevity? | The Peter Attia Drive Podcast

Peter Attia7m · 2022-05-17

Claims Made

15

Claims Supported

15

Support Rate

100%

Support rate

15 of 15 claims supported

15 supported0 partial / not

Claims from this content

11

✓Well SupportedThe largest reduction in all-cause mortality occurs when moving from the lowest fitness category to the next category.✓Well SupportedIndividuals in the top 2.3% of cardiorespiratory fitness have an 80% reduction in all-cause mortality compared to those in the bottom 25% of VO2 max.✓Well SupportedThe mortality reduction benefits of exercise are greater than those from quitting smoking or managing end-stage renal disease.✓Well SupportedImproving cardiorespiratory fitness can lead to significant improvements in mortality risk, comparable to or exceeding other major health interventions.Well Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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✓

Individuals with high blood pressure have a 21% greater risk of all-cause mortality compared to those with normal blood pressure.

✓Well SupportedVO2 max is a good predictor of all-cause mortality and cardiovascular disease mortality.

✓Well SupportedA VO2max test is recommended for benchmarking patients on their journey towards longevity goals.

✓Well SupportedIndividuals with end-stage renal disease have a 178% greater risk of all-cause mortality.

◐Partially SupportedIndividuals with coronary artery disease have a 29% greater risk of all-cause mortality compared to those without CAD.

◐Partially SupportedType 2 diabetes is associated with a 40% increase in mortality over a decade.

◐Partially SupportedEver having smoked tobacco is associated with a 41% increase in all-cause mortality over a decade compared to never smokers.