Andrew Huberman· PhD
Many people are taking BPC simply because they heard it’s good for them & helps “recovery” … & should ask “from what?”
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Many people are taking BPC simply because they heard it’s good for them & helps “recovery” … & should ask “from what?”
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Regenerative BPC157 is the biggie here.
Tons of anecdotal reports of people “healing faster”.
Essentially no human data.
BPC-157 is often used nowadays for wound and injury healing.
The “anecdata” circulating are enticing BUT there are real risks too; incl. possible tumor growth etc.
BPC157 & Injury Recovery
BPC-157 Healing, Patient Experiences
BPC-157, which is essentially a synthetic gastric juice that normally repairs the gut, being used to treat injuries.
Yeah, so BPC-157 is body protective compound 157. It's identical or bio-identical to gastric protective compound 157 that's produced in the stomach.
There is other uses of them, specifically in injuries. So I know that they've been studied, I'm not sure if it's in the military. We mentioned the woodpecker or the contrecoup injury. So that obviously.
And anecdotally, again, anecdotally, people report getting injections of this into the shoulder, knee, et cetera, and feeling so much better, so much faster, but there really aren't good studies, controlled studies.
what are your thoughts on bpc157 this is a gastric peptide that's now been synthesized so people will inject it into a tissue that they're trying to heal or improve lots and lots of anic data on
bpc157 this is a gastric peptide that's now been synthesized so people will inject it into a tissue that they're trying to heal or improve lots and lots of anic data on bpc157 making injuries heal faster Etc again anic data
in animal studies and I really want to emphasize animal studies because that's where the vast vast vast majority of data on bpc157 come from
bpc157 body protection compound 157 which is essentially a synthetic version of something found in gastric juice in all of us it's known that certain peptides within the gut that bpc 157 is known to mimic or actually is a synthetic version of that exact sequence or a portion of that sequence can assist in tissue and wound repair of different kinds tendon anything involving fiber blast all of that has been well demonstrated in vitro in a dish okay so not in Vivo as well as inv Vivo in certain cases but only in animal models
now again I do want to caution people that there is very little basically no evidence in humans besides the anecdotal evidence that people say they healed faster
now that using something intravenously from the pharmacokinetic standpoint it's not going to last in the system very more it's more of a spark whereas if you use an agent subcutaneously you're going to get more of a long lasting you know again not terribly long-lasting with peptides but longer than using something intravenously
there are many many animal studies on BPC57 showing accelerated cartilage growth nerve growth after injury and on and on and on and on and angiogenesis so there's some potential cancer risk there right but basically zero human data
but tons of people injecting and swallowing BPC and saying yeah it helped me recover you know heal more quickly
ipamrelin is a synthetic one but bpc157 occurs in the secretions of stomach lining there's bpc157 in our gut and
it's interesting like so bpc157 occurs in the stomach and the intestines or at least in the juices and people do uh people do eat like mondongo i think is intestines and then there's like all these other latin american dishes that are intestines i have intestines in my fridge in costa rica um and so and people do take bpc157 orally and i think it's mostly for gut issues but who knows
and bpc 157 was kind of a VF analog yeah that one is uh interesting cuz it's like pro-angiogenic so they're going to be you know pushing the whole you know it's going to cause cancer angle or it might so we can't really get behind it which understandable if it didn't make it through its trial so I get it at the same time it sucks though because it's like we've all used it or know someone who's used it who's had benefit from it with perceptively like no downside at least that we can see aute