Andrew Huberman· PhD
Caffeine sensitivity varies so much.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Caffeine sensitivity varies so much.
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Now there's caveats like everyone metabolizes caffeine differently You may be fast you may be slow but like generally speaking
There are people who can't have any coffee or chocolate or anything like green tea. Right. And they don't do well because they are slow caffeine metabolizers. And there are some people who really can have coffee right before bed, and they just process the stuff like it doesn't exist. And they get good quality sleep.
we know that people have different genes that are associated with the enzyme that decomposes caffeine and that's why some people are very caffeine sensitive or less
I've always felt like caffeine doesn't do anything to me I mean I love coffee so I make most days I'll make a coffee in the morning as French press more is the ritual and I just love the taste in the aroma but when I'm tired caffeine does not wake me up and it just seems to have zero impact on me in any way positive or negative
there are genetic differences in how quickly people metabolize caffeine and i think i'm someone who may be on the moderate end of the sensitivity spectrum
Some people they can drink an espresso, go to bed just fine. People metabolize it differently. Um, for some people 10 to 12 hours is actually too much. Um, where they need to stop in the morning or else there's just enough floating around in their system in the evening where they're not like jittery from caffeine, they just might have a harder time settling.