The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
if you eat a lot of meat and organs your creatinine may be above the reference range and that may be due to the breakdown of creatine into creatinine but that doesn't mean your kidneys are failing get a cystatin c in the past
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I've been recommending this to patients for 6 months now. The big shift is patients actually do it because the explanation is concrete.
Same in nutrition counseling. The before/after framing helps.
Tracking with a CGM on top of this for 3 months. Variability dropped quickly and stayed dropped.
Worth noting the 0.71 SMD in the Kreider meta is in trained athletes. Effect in untrained adults runs closer to 0.3 — still meaningful, but the panel should reflect that gradient.
Good catch. Could the brief surface the training-status interaction inline?
if you go to get a kidney test a comprehensive metabolic panel and your creatinine is quote unquote elevated or borderline elevated ask your doctor to get a catin c which is a metric of kidney function as well that is not dependent on the amount of creatine in your diet
if you're going to a doctor and getting your blood work most notably a comprehensive metabolic panel you want to get something called a cystatin c which is not affected by the amount of meat you're eating and will give you a good secondary indication of your kidney function
if you're going to a doctor and getting your blood work most notably a comprehensive metabolic panel you'll want to get something called a cystatin c which is not affected by the amount of meat you're eating and will give you a good secondary indication of your kidney function
if you are supplementing with creatine or you're eating a lot of meat make sure you get a catin c in addition to your creatinine so that your doctor doesn't freak out
The workaround is to ask your doctor for a test called a catin c which is not dependent on the amount of meat you're eating
you'll want to get something called a cyaten C which is not affected by the amount of meat you're eating and will give you a good secondary indication of your kidney function
so we've completely abandoned it so every time you order Labs on somebody and you see their creatinin it'll tell you what their estimated glal filtration for rate is we just ignore it completely we only look at saat and C MH so everything we do is based off that and there was a paper and jamama a couple of weeks ago that basically said as much which is maybe we should look more at cattin C instead of cron
please make this another reason to just look at cistatin C please I don't I I'm sure the test costs an extra dollar it's worth it cistatin C is a far more accurate way to measure and estimate GFR and you don't have this problem of getting the confounded creatine levels increased.
A more reliable marker of kidney function to use when taking creatine is cystatin C.
5 g of creatine monohydrate daily improves muscle strength and lean mass in healthy adults at standard training loads.
Creatine improves cognitive performance, especially under sleep deprivation and high cognitive load.
Creatine improves cardiovascular health markers and reduces all-cause mortality risk.
Creatine supports bone-mineral density in post-menopausal women when paired with resistance training.
Women need higher creatine doses (8–10 g/day) than men to reach the same intramuscular saturation.