Andrew Huberman· PhD
fasting can encourage things like autophagy, the engulfment of dead cells and things of that sort.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
fasting can encourage things like autophagy, the engulfment of dead cells and things of that sort.
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Many of you have probably heard of autoagi, which is essentially a cleaning up, a gobbling up of dead cells and cells that are injured or sick. And this is a natural process that occurs and it occurs mainly during sleep although not only during sleep. Fasting of any kind does tend to enhance autoagi.
fasting before sleep increases cellular cleanup, mitochondrial function and growth hormone release
fasting before sleep increases cellular cleanup, mitochondrial function and growth hormone release
Autophagy is clearing away those damaged cells we're talking about.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.