When you do lose weight, about 33% of that is lean body mass. And about 10% of fat cells, adipose cells are actually lean body mass as well, because it has proteins and water and things like that in it too
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
When you do lose weight, about 33% of that is lean body mass. And about 10% of fat cells, adipose cells are actually lean body mass as well, because it has proteins and water and things like that in it too
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
When we're talking to our patients, we want to limit lean loss to a quarter of the weight loss.
Lean losses are typically accounting for 1/2 to 2/3 of total weight loss.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.