Andrew Huberman· PhD
And I would say when it begins to matter is when you're older when you are in your 60s fat continuing to fast may be a negative negative for muscle muscle Health that first meal of the day is important
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
And I would say when it begins to matter is when you're older when you are in your 60s fat continuing to fast may be a negative negative for muscle muscle Health that first meal of the day is important
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an individual who is older or struggling to put on muscle fasting would not be my primary go-to I think that as individuals age there's a a bit of a a negative because you have to balance this muscle protein synthesis they're always going through a synthesis and a catabolism so an an anabolic process and a catabolic process as you age it becomes more difficult to regulate that process and if you add in additional fasting go through long periods of time where let's say you're not training you're not protecting skeletal tissue that would be a place where I don't necessarily recommend fasting
An individual who is older or struggling to put on muscle, fasting would not be my primary go-to.
three times fasting is not great for an aging population right it's just not the tissue is you're having trouble with it as is
but a younger healthier person is probably in a better position to weather them on and basically kind of benefit from the reduction of endotoxin but if you are older like especially if you have the the cycopenic obesity I mean raising cortisol is perhaps the worst thing you can do for such a person.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.