Andrew Huberman· PhD
So you think of the classic bodybuilder heart. It's an easy example to make. They have very thickened muscle. Their muscle is very strong, because they're pumping blood often with high blood pressure and that DHT and the testosterone and any DHT derivatives like Masteron or oxandrolone, preamble and also bind to the heart, and they cause even more hypertrophy or enlargement of that muscle tissue. So then let's say the person stops and they're recovering, and they're trying to have cardiac remodeling, which is where you take a very thick heart, and cardiac remodeling's important in a lot of different cardiac pathologies, but if you give them finasteride or dutasteride, which inhibit the enzyme that can converts testosterone to DHT, so making less activity at the androgen receptor gene, they have cardiac remodeling, and their heart health improves.