Andrew Huberman· PhD
Yeah, so hCG or human chorionic gonadotropin is actually very similar to TSH. - Thyroid stimulating hormone? - Correct, so when a woman is pregnant, she produces more hCG, especially in the first trimester.
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Yeah, so hCG or human chorionic gonadotropin is actually very similar to TSH. - Thyroid stimulating hormone? - Correct, so when a woman is pregnant, she produces more hCG, especially in the first trimester.
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So a quick points on hCG-- human chorionic gonadotropin-- made during especially the first trimester of pregnancy, it has effects other than binding to the LH receptor. It also binds to the TSH receptor in the thyroid. Yes. In fact, if you look at a molecule of hCG and thyroid stimulating hormone, they are extremely similar. However, you need a relatively high dose of hCG to bind to the TSH receptor. This is the normal mechanism in pregnancy that accounts for the increased need of thyroid hormone-- usually, about 30% to 40%.