Paul Saladino· MD
The answer is our massively increased and evolutionarily inconsistent consumption of linoleic acid!
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The answer is our massively increased and evolutionarily inconsistent consumption of linoleic acid!
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Excess linoleic acid from ALL sources leads to systemic insulin resistance.
i think that long-term chronic insulin resistance aka metabolic dysfunction is driven by excess linoleic acid in seed oils
i think that long-term chronic insulin resistance aka metabolic dysfunction is driven by excess linoleic acid in seed oils
but I think that the levels needed for optimal human physiology are much lower than what we consider today
I think seed oils are the single greatest driver of metabolic dysfunction insulin resistance diabetes eventually obesity in humans