The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And for instance, if a woman has just two or three follicles that are out each month, well, then the assumption-- again, it's just an assumption-- but the assumption that's pretty good-- because there is this positive correlation that generally occurs-- is that that ovarian reserve-- that the number of eggs in the vault is fairly low compared to someone who, say, has 20 follicles or 30 follicles each month.
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The way these are analyzed or measured is woman will go into the OB/GYN office, and by ultrasound-- typically there's some local anesthesia, but it's not often a general anesthesia, but by local anesthesia or sometimes no anesthesia-- they will essentially count the number of follicles that are present in each side, on ovary on the left and the ovary on the right, and give a woman some sense of how many follicles she has.
So the typical trend is for the number of antral follicles to decline over time. So one might expect, for instance, that a woman in her 20s or 30s might have 20, 30, maybe even 40 antral follicles that are exiting the reserve each month. And again, that's the total across both ovaries.
when you're 35 that number is closer to like 14 to 16
the number of eggs coming out of the vault is an indirect measure of how many eggs is in the vault when that number is going down it means the number of eggs in the vault is likely going down as well
when you're 44 2 to 4
what we should expect let's say in somebody who's 30 is you should have in the 16 to 20 range of total follicles per month right and left side combined
when you're 40 it's 8 to 10