Melatonin can be taken at the typical destination bedtime, potentially starting before departure, and should be continued for at least the first three nights for jet lag.

“Take melatonin in morning (versus at bedtime)”

“the melatonin thing I would stick with um I would stick with before bed like at typical bedtime right and you can even start that before you leave so you can actually take it before you leave for the whatever the destination is right and then you take melatonin at least for the first three nights”

“Strategic melatonin timing - A small dose of melatonin a couple of hours before you want to sleep helps signal to the brain it’s time to get ready for bed. This really helps when your internal clock thinks it is still daytime.”

“Take the melatonin at night to to cuz because you might still be producing some of the melatonin during your biological night, which is the environmental day, and not producing that melatonin at night when you want to be. So that's that's when you might supplement.”