Andrew Huberman· PhD
so we've got this drug we've got this drug metformin it's considered a perfect First Line agent for people with type 2 diabetes
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
so we've got this drug we've got this drug metformin it's considered a perfect First Line agent for people with type 2 diabetes
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and it’s one of the safest, cheapest drugs out there
Yeah, metformin's really interesting, because it's super safe. It's one of the safest drugs ever known. It's on the World Health Organization's List of Essential Medicines for humanity. In much of the world it's cost pennies, and you can get it over the counter-
metformin is typically first line I suspect part of that has to do with cost but I also believe it has to do with efficacy
Metformin remains an excellent, safe first-line therapy for type 2 diabetes.