We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
And there are some data as well and um Chris Master John talked about this recently um that if people are mitochondrial damage deficient, dealing with carbon monoxide poisoning, other metabolic issues that perhaps methylene blue because it can reroute some of the uh, the pathways for these electrons can be helpful. But if people are generally healthy that it can cause more problems than it solves.
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The data clearly shows that unless you have a block in your electron transport chain, it LOWERS ATP production in your mitochondria.
I'm not a fan of methylene blue I want people to understand this is not a healthy thing for humans yeah same all yeah yeah so methylene blue is is affecting your mitochondrial electron transport chain
if you have a healthy mitochondrial electron transport chain it's decreasing the amount of ATP you're producing that's been reproducibly shown so a healthy human is not benefiting from methylene blue
If you are generally healthy, if you don't have genetic defects in your mitochondrial electron transport chain, this is not for you.
Even if you're not the most metabolically healthy person, this is not the way to fix your mitochondria. A lot of people in the health space are saying that it improves mitochondrial function. Nothing could be further from the truth.
So, as we've seen, the way that you make ATP in the mitochondria is by moving electrons down the electron transport chain. In the process, protons are pumped from the inner part of the mitochondria, the matrix to the intermembrane space. The subsequent movement of those electrons down their concentration gradient through complex 5, which is also known as an ATP motor, is what generates ATP. Now, the electrons moving down the electron train creates the electrochemical potential that drives protons to the intermembrane space. And if you move the electrons down less of that chain, you move less protons into the inner membrane space and you have less protons creating ATP. So abbreviating the path of the electrons down the electron transport chain will cause less ATP to be produced. And that's what methylene blue does. It moves electrons further down the chain which can bypass a block in the chain if you have a pathology which very few people actually do but some people do.
I think for most of us, methylene blue is a net negative. And you should not be taking this. Don't take methylene blue unless you absolutely know that your mitochondrial electron transport chain is badly inhibited.
And the idea being circulated promugated online that methylene blue somehow optimizes mitochondrial function is completely wrong. Methylene blue absolutely does not optimize mitochondrial function unless you have a block in the electron transport chain in your body.
The idea that methylene blue improves the function of your mitochondria is really totally false. And I'm going to tell you why in a moment. I think most people are feeling a little bit better, maybe a little bit brighter or a different psychological state because of the ma inhibition. So if you are a generally healthy human, if you don't have clear blocks in your mitochondrial electron transport chain, methylene blue actually is hurting you. it is decreasing the amount of ATP produced in your mitochondria by moving electrons further down the electron transport chain.
I think most people who are taking methylene blue are decreasing the efficiency of ATP production, decreasing the amount of ATP produced in their body because you don't need to bypass those complexes in your mitochondrial electron transport chain.