Supplementing with 1,000 milligrams of EPA daily can allow individuals requiring prescription antidepressants to use lower doses of those medications.

“So I feel like more people should know about this. This is nutrition, but it's profoundly affecting mood and depression is terrible, right? Depression can have a component of anxiety in some cases where people are they feel lousy and very uncertain.”

“But what's interesting is this thousand milligrams per day or more of EPA has been shown to relieve both forms of depression.”

“More than a dozen studies have shown that ingesting at least 1,000 milligrams per day of the EPA form of essential fatty acid is as effective as prescription antidepressants in relieving depression.”

“Most people are not ingesting sufficient levels of omega-3, and I'm certainly one of those people. Despite an effort to eat good foods and whole foods, et cetera, and unprocessed foods, I've made the choice to ingest at least 1,000 milligrams per day of EPA.”

“And if you're somebody who requires prescription antidepressants, Prozac, Zoloft, et cetera, it can allow people to take lower doses of those medications, which in many cases is a positive thing or a good thing to do because of the side effect profiles that many of those drugs carry.”

“which is why I take a high-dose EPA.”

“getting above 1000 milligrams and probably even closer to 2000 milligrams per day of EPAs can be beneficial for mood, especially in attempts to treat or offset major depressive disorder.”

“Now, the threshold level seems to be about one gram, 1000 milligrams of EPA. So you will sometimes see on a bottle of krill oil or fish oil or any other source, even plant source or other source of EPA that it's 1000 milligrams or 1200 milligrams. But what's really important to look at is whether or not there's more than 1000 milligrams of EPA, because the EPA in particular is what's important here. [...] But people who took two grams seem to do better.”

“getting a one gram 1000 milligrams or more even as much as 2000 milligrams each day of the so-called EPA component of omega-3 fatty acids known to have antidepressant effects, mood elevating effects, known to have important effects protecting the cardiovascular system.”

“provided that one gets at least one gram of EPA, essential fatty acids, so it's not just getting one gram per day, but one or more grams per day of the EPA form of essential fatty acid, can rival some prescription antidepressants and/or decrease the amount of antidepressants that's required to take.”

“People that take these things in sufficient doses, meaning the EPAs, are able to get by with much lower dosages of SSRIs for depression relief or, in some cases, to come off their SSRIs completely or avoid going on antidepressant medication.”

“And so some people do that, and I've talked about before, how in double blind placebo controlled studies, people taking one to three grams of omega 3 fatty acids per day, typically in the form of a high quality fish oil, although there are other sources as well, algae and so forth, can experience improvements in mood that are on par with some of the SSRIs, the selective serotonin reuptake inhibitors.”

“fish oil, if taken at dosages of 1 to 3 grams of EPA per day, can have a mild to moderate antidepressant effect.”

“showing that it's at least as effective as certain SSRIs, antidepressants, at these dosages. And it can amplify or improve the effect of low dosages of some of these SSRIs.”

“um and there the recommendation is usually Target about a th000 milligrams of EPA of eicosapentanoic acid a day um if you're seeing some benefit but it feels like that there's more room for improvement so this is my mod I tell people then you could probably double it reasonably”

“and there the recommendation is usually Target about a th000 milligrams of EPA of eicosapentanoic acid a day um if you're seeing some benefit but it feels like that there's more room for improvement so this is my mod I tell people then you could probably double it reasonably”

“getting above a thousand milligrams, and probably even closer to 2,000 milligrams per day of EPAs, can be beneficial for mood, especially in attempts to treat or offset major depressive disorder.”

“you know some preliminary evidence randomized control trials small randomized control trials that need to be of course repeated with larger sample sizes you know they're basically showing that supplementation with EPA can help with depression”

“some Studies have suggested that high EPA fish oil often in the neighborhood of around 2 gam of EPA per day May itself have an effect on depression”