The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
It's usually, you know, it can go, depending upon if you get re-dosed or anything, go sometimes, depending upon how fast you metabolize it, sometimes 24, sometimes 36 hours. Sometimes it can be shorter, but it is a long time. It's a very long time. So it's definitely the longest acting psychedelic substance I know of.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And the reason why is because ibogaine is kind of the... Both seemingly the most potent and most seemingly, to me at least, most powerful psychedelic, but the one that has the most risk too, because it has a cardiac effect. It seems to be that you can screen people out that have risk off of their electrocardiogram and reduce the risk quite a bit.
ibigan um iboga it's a 22-hour long psychedelic Journey I've never done it truly where you close your eyes and and you get essentially real life like recollection of your experiences but you have agency inside these experiences there's some cardiac issues with abigan that require constant monitoring of the of the heart but they're they've got some really impressive outcomes this is all worked by my colleague Nolan Williams at Stanford
the kind of um Mount Everest of psychedelics which is under investigation by a colleague of mine at Stanford School of Medicine Nolan Williams is ibigan iboga which is 22 hours long it has cardiac effects this is not something to to get Cavalier with this is something only to be done in a clinical context with medical experts there
there are interesting studies of ibigan iboga where the universal uh experiences I understand is that PE it's 22 hours long it's actually a cardiovascular risk there's some things that need to be offset there so don't run out and do this folks but people I'm told get a highdefinition movie of specific events in their life that actually happened only when they close their eyes so no hallucinating with eyes open interesting and then they have agency within those movies and once they exact the change they wanted to have it rotates like a cube very interesting perhaps to a memory researcher why this would be and then they get another event of past where they have agency in that event incredible
And yeah, and ibogaine is a 22-hour psychedelic.