Paul Saladino· MD
there have been a few interventional studies where they actually gave me to people what do they show no increase in inflammatory markers no negative effects
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
there have been a few interventional studies where they actually gave me to people what do they show no increase in inflammatory markers no negative effects
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there are studies in which people have eaten more red meat and the inflammatory markers don't go up
is there any association with red meat for example no and heart disease no there's not an interventional studies so it's all epidemiology can right and it's all confounded by these healthy user and unhealthy user Pisces but there are no interventional studies which show that red meat is inflammatory
just like we shouldn't ignore the other randomized control trials that show that red meat is not inflammatory etc etc
there are no interventional studies with non-processed red meat that shows that it is inflammatory or harmful to humans in any way
Interestingly when interventional studies have been done red meat does not seem to increase the rates of cancer nor does it increase the rates of any cancer nor does it lead to inflammation nor does it lead to anything suggestive that it could be creating heart disease in humans
there are many animal studies and there are interventional studies in humans that suggest that red meat is not inflammatory that there's really no mechanistic basis by which red meat would cause cancer in the intestines
red meat has never been shown in an interventional study to worsen any of these metrics
i continue to uh to stand by my conviction that there are no short-term or moderate term studies that are interventional with red meat that show negative outcomes
the interventional studies that include more red meat in the diet do not show any problems
suggest that including a red meat an interventional manner not observational but interventional manner in the human diet leads to improvements in human health decreases in inflammatory markers like crp or tgf beta or il-6 and improvements in metabolic health
what we do have right off the bat I want to start with these two critical studies we have Interventional studies Interventional studies not observational studies where people are fed less red meat and rates of colon cancer are observed reasonably we should imagine that if red meat causes colon cancer and people with colon cancer or pre-cancerous lesions in their colons or people who are at risk of developing pre-cancerous lesions in their colons or colon cancer reduce their consumption of red meat you would see those colon cancers go down that is not what we see in Interventional studies
I showed Interventional studies showing that either increasing red meat does not increase markers of inflammation or oxidative stress or decreasing red meat does not change colon cancer outcomes or liver fat and glucose control outcomes
you look at the research you're not going to find a single Interventional study that shows red meat causes hypertension you're not going to find a single Interventional study that shows red meat causes inflammation you're not going to find a single Interventional study that shows that red meat causes atherosclerosis