Andrew Huberman· PhD
because adipose fat tissue can convert testosterone into estrogen. So it sounds like, except in special cases, that avoiding aromatase inhibitors is probably going to be a good idea.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
because adipose fat tissue can convert testosterone into estrogen. So it sounds like, except in special cases, that avoiding aromatase inhibitors is probably going to be a good idea.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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similarly aromatase activity varies genetically but it also varies by factors such as insulin resistance obesity and factors like that and therefore the more adipose tissue you have typically the more aromatase you have so a person who's overweight is going to make more estradiol all things equal from a given amount of testosterone than a person who is lean
similarly aromatase activity varies genetically but it also varies by factors such as insulin resistance obesity and factors like that and therefore the more adipose tissue you have typically the more aromatase you have so a person who's overweight is going to make more estradiol all things equal from a given amount of testosterone than a person who is lean