Paul Saladino· MD
in people or patients or individuals with glucose 6-phosphate dehydrogenase deficiency it can actually have a hemolytic effect
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
in people or patients or individuals with glucose 6-phosphate dehydrogenase deficiency it can actually have a hemolytic effect
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high doses of vitamin C also become Pro oxidants yeah this is a crazy thing so there's a condition called g6pd deficiency glucose 6-phosphate dehydrogenase deficiency which illustrates this very well if you give high doses of vitamin C to somebody with g6pd deficiency you will cause mollis
if you give someone with g6pd high doses of vitamin C they will get hemolysis a gram two grams of vitamin C can cause hemolysis and some of the g6pd to me suggesting that's a pro-oxidant
meaning that they couldn't find any evidence I mean this is again the 1930s and 1940s so what kind of blood tests were they doing but they couldn't find any evidence of any benefits of vitamin C above ten milligrams a day so this gets into this really kind of counterculture notion like are we really using vitamin C as an antioxidant as much as people think we are this is the Linus Pauling theory that mega doses of vitamin C are good for us which I would argue very strongly with and most people when they take vitamin C will take a thousand milligrams which is potentially you know a hundred times more than they need in a day and can have serious consequences for people with g6pd or glucose 6-phosphate dehydrogenase deficiency we know that that much vitamin C can cause hemolysis we're getting a little bit granular here but what we see is that vitamin C can turn into an anti can turn into an oxidant molecule rather than an anti oxidant high doses
and we know that it can have pretty bad side effects in some people
people who have a deficiency in the enzyme glucose 6-phosphate dehydrogenase could be at risk of hemolysis the rupturing of red blood cells when given high doses of intravenous vitamin C
Some serious side effects have been reported with high-dose intravenous vitamin C in patients with cancer
Some serious side effects have been reported with high dose intravenous vitamin C in patients with cancer in addition people who have a deficiency in the enzyme glucose 6-phosphate dehydrogenase are at risk of hemolysis the rupturing of red blood cells when given high doses of intravenous vitamin c