Paul Saladino, MD Is Nose to Tail Carnivore the Optimal Human Diet?

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Paul Saladino1h 10m · 2019-07-16

Claims Made

154

Claims Supported

100

Support Rate

65%

Support rate

100 of 154 claims supported

100 supported54 partial / not

Claims from this content

124

Well SupportedAll vitamins and minerals found in plants can be obtained from animal sources in more bioavailable forms.Well SupportedIt is possible to obtain 60 mg of vitamin C daily by eating animal foods nose-to-tail, with liver being richer in vitamin C than muscle meat.Not SupportedMetabolic health context is crucial for understanding atherosclerosis, not just LDL's direct injury to the endothelium.Well SupportedConsuming connective tissue provides glycine and helps maintain a healthy methionine-to-glycine ratio.Well Supported

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Thousands of people are following a carnivore diet and experiencing changes in various diseases, including autoimmune disease.

Well SupportedThe carnivore diet helped the speaker heal eczema by removing potential plant triggers and taught them about bioindividuality.

Well SupportedA vitamin C dose as low as 10 milligrams per day was sufficient to correct scurvy in studies from the 1930s and 40s, with no observed clinical benefit from higher doses.

Well SupportedOverfeeding mice with methionine shortens their lifespan, and restricting methionine in mice extends their lifespan.

Well SupportedA carnivore diet can lead to lower rates of depression and improved mood stability, emotional resilience, and overall positivity.

Not SupportedHigh doses of vitamin C can act as pro-oxidants in individuals with G6PD deficiency, potentially causing hemolysis.

Well SupportedEliminating plants from the diet has been associated with improvements in inflammatory bowel disease and other conditions in case reports.

Well SupportedA well-constructed carnivore diet following a nose-to-tail template is the ideal diet for all humans, with some individuals able to tolerate additional plant foods.

Not SupportedHigh meat consumption in Hong Kong does not contradict the idea that meat absence is associated with longevity.

Not SupportedThe evidence for fiber preventing colon cancer is non-existent, with studies showing no change in the recurrence rate of colonic adenomas with fiber supplementation.

Well SupportedCollagen from animal connective tissue can be fermented into short-chain fatty acids.

Well SupportedNose-to-tail eating may be a significant lever for achieving health, potentially more so than conventional medical approaches.

Not SupportedThe assertion that plant fiber is necessary to prevent the digestion of the mucus layer in the gut has not been demonstrated.

Well SupportedIndividuals on ketogenic diets may need to increase salt intake due to insufficient insulin signaling at the kidney for electrolyte retention.

Well SupportedLiver is rich in copper and complements muscle meat, which is high in zinc, and both are needed.

Well SupportedPaul Saladino has been over 90% carnivore, including organ meats daily, since a hunting trip.

Not SupportedWestern medicine often fails to appreciate the profound impact of food on inflammatory, autoimmune, dermatological, and psychiatric diseases.

Well SupportedSleep, diet, and exercise are the interventions with the biggest impact on health that are accessible and within people's control.

Well SupportedAn elimination diet is a tool for identifying how specific foods affect an individual.

Not SupportedWestern medicine often errs by addressing symptoms with medications without tackling the fundamental imbalance that caused the illness, leading to future health issues.

Well SupportedEliminating vegetables can improve gastrointestinal issues like gas, bloating, constipation, and painful stools for some individuals.

Well SupportedButyrate is not the only short-chain fatty acid usable by colonic epithelial cells and can be produced in low or zero fiber environments.

Well SupportedFood is a significant factor in influencing health and causing or resolving illnesses.

Not SupportedPaul Saladino experienced eczema within four days of consuming raw goat's milk, indicating sensitivity to A2 dairy.

Well SupportedAn omega-6 to omega-3 fatty acid ratio of approximately 4:1 or less is desirable for reducing inflammation.

Not SupportedFiber is not supported by clinical studies for constipation resolution.

Not SupportedIncreasing fiber intake is not necessarily required for a healthy microbiome, and decreasing fiber does not automatically lead to an unhealthy microbiome.

Well SupportedMost chronic illness is inflammatory, and inflammation and autoimmunity are considered synonymous.

Partially SupportedCollagen and bone broth are valuable for humans, with collagen being referred to as the 'fourth macronutrient'.

Partially SupportedFunctional medicine focuses on identifying and treating the root cause of illness rather than just ameliorating symptoms.

Well SupportedFiber intake decreases the risk of diverticulitis, a potential risk factor for developing colon cancer.

Well SupportedIndividuals who consume animal foods nose-to-tail and supplement with collagen are likely to have a health advantage over those who only eat muscle meats.

Partially SupportedMilk from animals other than cows (goats, buffalo, camels) is naturally A2.

Partially SupportedA carnivore diet provides all necessary nutrients for optimal human function in the most bioavailable form.

Partially SupportedThe author transitioned to a carnivore diet after 10-12 years on a primal/paleo diet due to unresolved eczema.

Partially SupportedHistorically, dairy consumed by various cultures was raw, and cows may have been of the A1 or A2 genetic lineage.

Partially SupportedEffective longevity and health practices align with ancestral human behaviors.

Partially SupportedIncreased plant and vegetable intake is correlated with decreased sperm quality.

Partially SupportedExcluding carbohydrates can lead to improved mental clarity for some individuals.

Partially SupportedThe need for certain electrolytes, like salt, increases on a ketogenic diet.

Partially SupportedAnimals in the wild seek out salt, even at the expense of other needs.

Partially SupportedThe requirement for vitamin C may decrease on low carbohydrate or ketogenic diets because sugar competes with vitamin C for cellular uptake.

Partially SupportedMainstream psychiatric training does not teach that psychiatric illness is inflammatory or involves immune system activation in the brain.

Partially SupportedA carnivore diet may resolve autoimmunity.

Partially SupportedA well-constructed carnivore diet is an ideal human diet and is often the end result of elimination diets.

Not SupportedIndividuals on a carnivore diet may be missing necessary nutrients if they are not eating nose-to-tail, particularly fats.

Partially SupportedStudies from the 1960s and 1970s showed that psychiatric patients on gluten-free diets improved compared to those on gluten-containing diets.

Partially SupportedThe speaker transitioned through various restrictive diets (Paleo, Autoimmune Paleo, low oxalate, low histamine, low lectin) before trying a carnivore diet.

Partially SupportedThere is a dietary etiology to schizophrenia.

Partially SupportedKetogenic diets can generally promote autophagy, and incorporating fasting may further enhance this process.

Partially SupportedMany perceived lactose intolerances are actually intolerances to A1 casein.

Partially SupportedLow salt diets may be associated with insulin resistance, and a meat-based diet would likely provide adequate potassium.

Not SupportedEarly scientific investigations misclassified Paleo diets as 'low-carb' despite containing up to 30% of calories from carbohydrates.

Not SupportedExpansion of the small intestine and colon due to bulking fibers can lead to pouching, disruption of the lining integrity, and diverticula formation.

Not SupportedA1 casein variant in dairy breaks down into beta-casomorphin 7, which may trigger autoimmunity and issues for people.

Not SupportedThe idea that food has no effective role in health is ludicrous.

Partially SupportedEating the whole animal, including fat, connective tissue, and organs, naturally provides necessary nutrient ratios without the need for supplements or complex calculations.

Partially SupportedA systematic reintroduction of foods after a simple diet can help identify individual food responses.

Partially SupportedRecommended Daily Allowances for nutrients were initially based on a largely carbohydrate-based diet, and the body's needs shift with carbohydrate consumption and fat intake.

Partially SupportedPatients in inpatient psychiatric facilities are often fed triggering foods like oatmeal, orange juice, and jello.

Partially SupportedEating clean 90% of the time with 10% social indulgences may achieve the highest quality of life.

Not SupportedThe LDL-lowering effect of fiber is minuscule and not statistically significant for blood pressure.

Partially SupportedMetabolic flexibility, achieved by deriving energy from stored body fat instead of needing to eat carbohydrates, is a significant factor in managing the human tendency to overeat.

Partially SupportedSome individuals report increased food sensitivity after adopting a carnivore diet, which may be due to becoming more aware of pre-existing sensitivities.

Partially SupportedMental clarity and mood enhancement benefits observed with some diets, including carnivore, may be due to the elimination of offending agents rather than specific macronutrient profiles like ketosis.

Partially SupportedPaul Saladino does not take vitamin C supplements and believes lower doses than recommended are adequate for his needs.

Not SupportedSupplementation with only alpha-tocopherol vitamin E can be counterproductive and pro-oxidant if it creates an imbalance with other tocopherol forms.

Partially SupportedFava beans contain a pro-oxidant molecule that can cause red blood cell hemolysis in individuals with G6PD deficiency.

Partially SupportedThe primary function of bowel movements may be to eliminate dead bacteria.

Partially SupportedEating only tenderloin and avoiding other animal parts has negative health consequences.

Partially SupportedMainstream psychiatric training does not currently recognize the impact of ketogenic diets.

Partially SupportedOrgan meats like liver contain copper, which is necessary to balance zinc intake.

Partially SupportedGluten intake can trigger psychosis in susceptible individuals.

Partially SupportedSalt is a critical mineral for human survival.

Partially SupportedWestern medicine has historically been unable to resolve autoimmune diseases like juvenile rheumatoid arthritis, Crohn's disease, colitis, and psoriasis.

Partially SupportedA low-fiber diet shifts gut bacteria towards strains that ferment fat or use protein.

Partially SupportedA carnivore diet can serve as an elimination diet.

Partially SupportedAutoimmune conditions may be a root cause of hypertension in many cases.

Partially SupportedLimiting salt in individuals with high blood pressure may cause compensatory renin-angiotensin-aldosterone activity that raises blood pressure.

Partially SupportedHigh amounts of salt are not the cause of high blood pressure.

Partially SupportedStudies from the 1950s-1980s suggest nutritional interventions can be effective for psychiatric illness.

Partially SupportedHistorically, humans likely consumed very small amounts of vitamin C, possibly only from animal sources, and it is difficult to obtain large amounts even from fruits today.

Partially SupportedThere is no evidence from interventional studies that supplemental vitamin C provides benefits beyond preventing scurvy.

Partially SupportedInformation about the health consequences of poor lifestyle choices is available, and individuals are responsible for their choices if they later regret them.

Partially SupportedImplementing diets like Paleolithic, primal, or carnivore in inpatient psychiatric facilities could be a powerful intervention for patients.

Partially SupportedThe pathology of diverticulosis may be autoimmune, evidenced by lymphocytic infiltration, rather than solely due to intraluminal pressure from fiber.

Partially SupportedHeme iron can become problematic if consumed in excess by individuals without a proper disposal mechanism, but this risk can be mitigated by balancing it with other minerals.

Partially SupportedThe internet and social media enable large-scale health studies and data collection without formal oversight from institutions like the NIH.

Partially SupportedHuman nature includes a predisposition to overeat and to consume foods up to the limit of what can be tolerated without immediate negative consequences.

Partially SupportedThe mucus layer in the colon acts as a protective barrier between colonic epithelial cells and bacteria, preventing constant contact.

Partially SupportedDiverticulosis may be autoimmune, evidenced by lymphocytic infiltration in the cecum.

Partially SupportedMany chronic diseases may be autoimmune or inflammatory in nature.

Not SupportedDiets that are not sufficiently low in carbohydrates may result in negative effects from both meat consumption and inadequate carbohydrate restriction.

Partially SupportedAnecdotal evidence suggests potential benefits of a vegan diet for autoimmune diseases.

Partially SupportedHigh vitamin C requirements may be a consequence of high sugar intake, as sugar and vitamin C compete for the same receptor sites.

Partially SupportedHigh consumption of vitamin C can cause damage requiring glutathione regeneration, even in individuals without G6PD deficiency.

Partially SupportedHigh TMAO levels are caused by diabetes and chronic kidney disease, not the other way around.

Not SupportedThe argument that fiber lowers LDL cholesterol is flawed because it relies on the cholesterol theory of heart disease, which is highly debated.

Partially SupportedThe methionine and glycine ratio in collagen is a key factor.

Not SupportedInsoluble fiber does not 'scour' the intestines.

Partially SupportedAnecdotal evidence suggests carnivore diets can resolve psychiatric disease and polycystic ovarian syndrome.

Partially SupportedActivated charcoal can mitigate potential negative effects from occasional dietary indulgences.

Partially SupportedA 1980s study at Mass General showed phosphatidylcholine significantly improved bipolar patients.

Partially SupportedCholine, a precursor for cell membranes, can be obtained from egg yolks, liver, and grass-fed muscle meat.

Partially SupportedIndividuals have control over many factors that contribute to health problems, including diet, sun exposure, and movement.

Partially SupportedIndividuals can consistently achieve the highest quality of life by switching back to a healthier diet after occasional indulgences.

Partially SupportedThe resolution of autoimmune disease is considered a significant goal in medicine.

Partially SupportedCholine and carnitine are vital nutrients for brain and membrane health.

Not SupportedLimiting salt intake can be more harmful than beneficial for individuals with high blood pressure.

Partially SupportedGlutathione is the body's main resident antioxidant system and requires NADPH for regeneration.

Partially SupportedEczema is an autoimmune disease of the skin, similar to psoriasis but with different pathology.

Partially SupportedIf an individual consumes a food identified as a trigger for discomfort after an elimination diet, they are responsible for negative consequences.

Partially SupportedModern Westernized diets make it difficult to distinguish between beneficial food signals and subtle negative effects.

Partially SupportedCertain bulking fibers consumed with water expand to aid digestion and elimination.

Partially SupportedThe necessity of vegetables may be reconsidered if micronutrients can be adequately obtained from high-quality animal foods.

Partially SupportedLow carbohydrate and ketogenic diets may change the body's requirements for certain nutrients.

Partially SupportedThe concept of toxicity is dose-dependent, as seen with the zinc and copper ratio, where excess zinc can lead to copper deficiency.

Partially SupportedPractices like walking barefoot, sun exposure, contact with dirt, and swimming in cold water are ancestral health practices.

Partially SupportedSome individuals may feel better on a low-lectin primal diet, while others may feel better without any plants.

Partially SupportedElimination diets are powerful interventions in functional medicine.